Laboratory of Structural & Supramolecular Chemistry

Research Projects

 

References: C.  Structure of macromolecules by X-ray crystallography

 

  1. “The binding of beta and gamma-cyclodextrins to glycogen phosphorylase b: kinetic and crystallographic studies” N. Pinotsis, D. D. Leonidas, E. D. Chrysina, N. G. Oikonomakos, I. M. Mavridis, Protein Sci. 2003, 12, 1914-1924.
  1. P. Zou, N. Pinotsis, S. Lange, Y-H. Song, A. Popov, I. Mavridis, O. M. Mayans, M. Gautel, M. Wilmanns “Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk” Nature, 439, 225-228 (2006).
  2. The structure of the 360 Å long C-terminal muscle filament of myomesin,derived from a combined crystallographic and small-Angle X-ray scattering analysis” S.D. Chatziefthimiou, J.A. Zoidberg, D.I. Svergun, I.M. Mavridis, M. Wilmanns, N. Pinotsis, XXI Congress of the Int. Union of Crystallography, Osaka, Japan, Aug. 23-31, 2008.

  1. P. Giastas, N. Pinotsis, G. Efthymiou, M. Wilmanns, P. Kyritsis, J- M. Moulis, I. M. Mavridis “The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32 Å resolution. Comparison with other high resolution structures of ferredoxins and contributing structural features to reduction potential values”, J. Biolog. Inorg. Chem. 11, 445-458 (2006).
  1. E. Saridakis, P. Giastas, G. Efthymiou, V. Thoma, J-M. Moulis, P.Kyritsis, I. M. Mavridis "Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: Crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin" J. Biol. Inorg. Chem.14, 783-799 (2009).
  1. Naomi E. Chayen & Emmanuel Saridakis “Protein crystallization: from purified protein to diffraction-quality crystal.” Nature Methods (2008) 5, 147-153.
  1. Emmanuel Saridakis & Naomi E. Chayen “Towards a ‘universal’ nucleant for protein crystallization.” Trends Biotechnol. (2009) 27, 99-106.

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