Laboratory of Structural & Supramolecular Chemistry



  1.    D. Mentzafos, I. M. Mavridis, G. Le Bas and G.Tsoucaris "The Crystal Structure of the 4-tert-Butylbenzyl Alkohol β -Cyclodextrin Complex. Common Features in the Geometry of the β -cyclodextrin Dimeric Complexes", Acta Crystallogr. 1991, B47, 746-757.

  2.  I.M. Mavridis, E. Hadjoudis and G. Tsoucaris "The Crystal Structure of the Inclusion Complex of Cyclomaltoheptaose (β -cyclodextrin) with 3,3-Dimethylbutylamine", Carbohydr. Res. 1991, 220, 11-21.

  3. E. Hadjoudis, I. Argyroglou, E. Lambi and I. Moustakali-Mavridis "Structural-Directing Effects in the Photochromism of Anils" Molecular Engineering 1991, 1, 67-74.

  4.  I.M. Mavridis and   E. Hadjoudis "The Crystal Structure of the Inclusion Complex of Cyclomaltoheptaose (β -cyclodextrin) with 4-tert-Butyltoluene", Carbohydr. Res. 1992, 229, 1-15.

  5.  A. Botsi, K. Yannakopoulou, E. Hadjoudis "Inclusion Complexes of Cyclomaltoheptaose (β-cyclodextrin) and its Methylated Derivatives with the Main Components of the Pheromone of the Olive Fruit Fly", Carbohydr. Res. 1993, 241, 37.

  6.   A. Botsi, K. Yannakopoulou, E. Hadjoudis and B. Perly "NMR Differentiation of Enantiomeric (+)- and (-)-α-Pinene via Complexation with Cyclodextrins in Water", J. Chem. Soc. Chem. Commun. 1993, 1085.   

  7.  E. Gogolides, K. Yannakopoulou, A. Traverse, A. G. Nassiopoulos, E. Tsoi, M. Hatzakis "Characterization of a Positive-tone wet Silylation Process with the AZ 5214TM Photoresist",  Microelectronic Engineering, 1994, 25, 75-90.

  8.    E. Gogolides, K. H. Baik, K. Yannakopoulou, L. Van den hove, M. Hatzakis "Lithographic Evaluation of a New Wet Silylation Process Using Safe Solvents and the Commercial Photoresist AZ 52314 TM",  Microelectronic Engineering,  1994, 23, 267.

  9.     A.Rontoyianni, E. Hadjoudis and I. M. Mavridis, "Solid State Photochromism and Thermochromism of N-(5-bromo-salicylidene)-2-phenylethylamine ", Mol. Cryst. Liq. Cryst. 1994, 242, 221-226.

  10.     G. Pistolis, E. Hadjoudis and I. M. Mavridis, "Photoactivity within Cyclodextrin Cavities: Inclusion Complexes of Anils with Cyclodextrins" Mol. Cryst. Liq.Cryst. 1994, 242, 215-219.

  11.    I.M. Mavridis, D. Mentzafos and H. Schenk, "Crystal Structure of the Heptakis (2,3,6-tri-O-methyl)-β-cyclodextrin Complex with Ethyldodecanoate Ester", Carbohydr. Res. 1994, 253, 39-50.

  12.    A.Rontoyanni, I. M. Mavridis, E. Hadjoudis and A. J. M. Duisenberg, "The Crystal Structure of the Inclusion Complex of Cyclomaltoheptaose with 4-tert-Butylbenzoic acid", Carbohydr. Res. 1994, 252,19-32.

  13.     A.Rontoyanni and I. M. Mavridis, "The Crystal Structure of the inclusion Complex of Cyclomaltoheptaose (β -cyclodextrin ) with 3,5-Dimethylbenzoic Acid", J Inclus. Phenom. 1994, 18, 211-227.

[top of page]


  1.    I.Smonou, S. Khan, C. S. Foote, Y. Elemes, I. M. Mavridis, A. Pantidou, M. Orfanopoulos "Reactions of Phenyltriazolinedione with Alkenes. Stereochemistry of the Methanol Adducts to Aziridinium Imine Intermediates", J. Am. Chem. Soc. 1995, 117, 7081-7087.

  2.     M. Arkas, K. Yannakopoulou, C. M. Paleos, P. Weber and A. Skoulios "The Mesomorphic Behaviour of Cyanopropylalkyldimethylammonium Bromides", Liq. Cryst. 1995, 18, 563.

  3.     Botsi, K. Yannakopoulou, B. Perly and E. Hadjoudis "Positive or Adverse Effects of Methylation on the Inclusion Behaviour of Cyclodextrins. A Comparative NMR Study Using Pheromone Constituents of the Olive Fruit Fly", J. Org. Chem., 1995, 60, 4017.

  4.     A.Botsi, K. Yannakopoulou, B. Perly and E. Hadjoudis "Structural Aspects of Permethylated Cyclodextrins and Comparison to their Parent Oligosaccharides, as Derived from Unequivocally Assigned 1H and 13C NMR Spectra in Aqueous Solutions", Magn. Reson. Chem. 1996, 34, 419-423.

  5.    Botsi, K. Yannakopoulou,  E. Hadjoudis, and J. Waite "AM1 Calculations on Inclusion Complexes of Cyclomaltoheptaose (β-Cyclodextrin) with 1,7-Dioxaspiro[5.5]undecane and Nonanal, and Comparison with Experimental Results", Carbohydr. Res., 1996, 283, 1-16.

  6.     D. Mentzafos and I. M. Mavridis, “β -Cyclodextrin (Z)-9-Dodecen-1-ol 2:1 Complex”, Acta Crystallogr. 1996, C52, 1220-1223.

  7.    A.Rontoyanni and I. M. Mavridis, “β -Cyclodextrin Nonanoic Acid 1:1 Complex”, Acta Crystallogr. 1996 C52, 2277-2281.

  8.    K. Yannakopoulou, D. Mentzafos, I. M. Mavridis and K. Dandika “Chiral Recognition of (R)-(_)-1,7-Dioxaspiro[5.5]undecane by Hexakis(2,3,6-tri-O-methyl)-α-Cyclodextrin”, Angew. Chem. Int. Ed. Engl. 1996, 35, 2480-2482.

  9.     E. Eliopoulos and I. M. Mavridis “Molecular Graphics Approaches in Structure Prediction and Determination”, in Crystallography of Supramolecular Compounds, Ed. G.Tsoucaris, J. L. Atwood and J. Lipkowski, NATO ASI, 1996, 480, 491-498, Kluwer Acad. Publ.

  10.     E. Eliopoulos and I. M. Mavridis, “An Interactive-Kinetic Approach to the Study of Supramolecular Structures”, in Crystallography of Supramolecular Compounds, Ed. G.Tsoucaris, J. L. Atwood and J. Lipkowski, NATO ASI, 1996, 480, 499-511, Kluwer Acad. Publ.

  11.   Α.Rontoyianni and I. M. Mavridis, R. Israel, G. Beurskens, ‘The Crystal Structure of the Heptakis(2,3,6-tri-O-methyl)-ß-cyclodextrin with Methylcyclohexane’, J. Inclus. Phenom. 1998, 32, 415-428.

  12.    S. Makedonopoulou, I. M. Mavridis, K. Yannakopoulou, J. Papaioannou, ‘Organization of Long Aliphatic Monocarboxylic Acids in β-Cyclodextrin Channels. Crystal Structures of the Inclusion Complexes of Tridecanoic Acid and (Z)-tetradecenoic Acid in β-Cyclodextrin’, J. Chem. Soc. Chem. Commun. 1998, 2133-2134.

  13.     K.G. Fournaris, M.A. Karakassides, D. Petridis and K. Yannakopoulou “Clay Polyvinyl pyridine nanocomposites” Chemistry of Materials, 1999, 11, 2372-2381.

  14.   I.M. Mavridis, “Influence of the Guest on the Packing of Dimeric β-Cyclodextrin Complexes”, in Current Challenges on Large Supramolecular Assemblies, Ed. G.Tsoucaris, , NATO ARW, 1999, 403, pp 393-Kluwer Acad. Publ.

  15.     D. Mentzafos, I. M. Mavridis and K. Yannakopoulou, ‘Structure of Permethylated α-Cyclodextrin (R)-(_)-1,7-Dioxaspiro[5.5]undecane 1:1 Complex’, J.  Inclus. Phenom. 1999, 33, 321-330.

  16.     Α.Rontoyianni, I. M. Mavridis, ‘Dimeric Complex of Alpha-cyclodextrin with 1,12-Diaminododecane. Comparison with other Alpha Cyclodextrin Dimeric Complexes’, Supramol. Chem. 1999, 10, 213-218.

  17.    Κ. Eliadou, K. Yannakopoulou, A. Rontoyianni, I. M. Mavridis, ’NMR Detection of Simultaneous Formation of [2]- and [3]Pseudorotaxanes in Aqueous Solution between α-Cyclodextrin and Linear Aliphatic α,ω-Aminoacids, an α,ω-Diamine and an α,ω-Diacid of Similar Length, and Comparison with The Solid State Structures’,  J. Org. Chem. 1999, 64, 6217-6226.

  18.     S. Makedonopoulou, A. Tulinsky, I. M. Mavridis, ‘The Dimeric Complex of β-cyclodextrin with 1,13-tridecanedioic acid’, Supramol. Chem. 1999,11, 73-81.   

  19. J. Papaioannou, N. Papadimitropoulos, I. M. Mavridis, ‘Dielectric Relaxation of β-Cyclodextrin Complex with 4-t-butyl-Benzyl Alkohol’, Mol. Phys. 1999, 97, 611-627.

  20.     E. Hadjoudis, I. M. Mavridis, T. Dziembowska, Z. Rozwadowski and R. Anulewicz, ‘Spectroscopic and Structural studies of the Thermochromism of Solid Di-anil of 2-Hydroxy-5-methyl-isophthalaldehyde’, Molecular Engineering 1999, 8, 97.

[top of page]


  1.   S. Makedonopoulou, J. Papaioannou, I. Argyroglou, I. M. Mavridis “Crystal Structure of the Inclusion Complex of β-Cyclodextrin with the Aliphatic monoacids Tridecanoic Acid and (Z)-Tetradecenoic Acid. Formation of [3]PseudorotaxanesJ. Inclus. Phenom. 2000, 36,191-215. Cover of the issue   

  2. S. Makedonopoulou, I. M. Mavridis “Structure of the Inclusion Complex of β-Cyclodextrin with 1,12-Dodecanodioic Acid using Synchrotron Radiation Data. A Detailed dimeric β-Cyclodextrin Structure”, Acta Crystallogr. 2000, B56, 322-331.

  3.    S. Makedonopoulou, K. Yannakopoulou,  D. Mentzafos, V. Lamzin, A. Popov,  I. M. Mavridis “Non-covalent Interactions in the Crystallization of the Enantiomers of 1,7-Dioxaspiro[5.5]undecane (Olive Fly Sex Pheromone) by Enantiospecific Cyclodextrin Hosts, Hexakis(2,3,6-tri-O-methyl)-α-cyclodextrin and Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin” Acta Crystallogr. 2001, B57, 399-409.

  4.    A.Kokkinou, K. Yannakopoulou, I. M. Mavridis, D. Mentzafos “Inclusion Compounds of Plant Growth Regulators in Cyclodextrins. Part II. Structure of the Complex of β-Cyclodextrin with β-Naphthyloxyacetic acid in solid state and in aqueous solution” Carbohydr. Res. 2001, 332, 85-94.

  5.    A.Tsortos, K. Yannakopoulou, K. Eliadou, I.M. Mavridis and G. Nounesis “Partial Thermal Dethreading of [3]pseudorotaxanes of α-Cyclodextrin with Linear Aliphatic α,ω-Aminoacids in Aqueous Solution”, J. Phys. Chem. 2001, B105, 2664-2667.  

  6. S. Makedonopoulou, I. M. Mavridis “The dimeric complex of beta cyclodextrin with 1,14-tetradecanedioic acid. Comparison with related complexes”, Carbohydr. Res 2001, 335, 213-220.

  7.    K. Yannakopoulou, J. A. Ripmeester, I. M. Mavridis “Release of the Prays Oleae Pheromone, as a Consequence of Supramolecular Structure: Study of the β-Cyclodextrin/(Z)-7-Tetradecenal complex by X-ray crystallography and by NMR spectroscopy in the solid state and in solution” J. Chem. Soc. Perkin Trans. 2 2002, 1639-1644.

  8.    D. Zouvelekis, K. Yannakopoulou, I. M. Mavridis E. Antoniadou-Vyza, The self-association of the drug acemethacin and its interactions and stabilization with β-cyclodextrin in aqueous solution as inferred from NMR spectroscopy and HPLC studies”, Carbohydr. Res. 2002, 337, 1387-1395.

  9.    J. C. Papaioannou, T. C. Ghikas, I. M. Mavridis “Dielectric relaxationof the β-cyclodextrin complexes with tridecanoic acid and 1,13-tridecanedioic acid”, J.  Inclus. Phenom. 2002, 43, 107-113.

  10.    N. C. Papandreou, S. Makedonopoulou, E. Antoniadou-Vyza, I. M. Mavridis, S. J. Hamodrakas, 2,4-Diamino-5-(1-naphthyl)-3,5-diaza-1-azoniaspiro [5.5]undeca-1,3-diene chloride” Acta Crystallogr. 2002, C58, 730-732.

  11.    P. Giastas, N. Mourtzis, K. Yannakopoulou and I. M. Mavridis “Pseudorotaxanes of β-Cyclodextrin with Diamino End-functionalized Oligo-phenyl and -benzyl Compounds in Solution and in the Solid State”, J.  Inclus. Phenom. Macrocycl. Chem. 2002, 44, 247-250.

  12.    K. Eliadou, K. YannakopoulouNMR Spectral Assignment of Per-substituted Key-Intermediates of bCD and Implications in the Structures of the Derivatives”, J. Inclus. Phenom. Macrocyclic. Chem., 2002, 44, 247.

  13.     N. Mourtzis, G. Cordoyiannis, G. Nounesis, K. Yannakopoulou “Rotaxanation of Congo Red into γ-Cyclodextrin. Solution Structures and Thermodynamic Parameters of 1:1 and 2:2 Adducts, as Obtained from NMR Spectroscopy and Microcalorimetry”, Supramolecular Chem. 2003, 15, 639-649.

  14.     M. Yagi, S. Hirano, S. Yoyota, F. Toda, P. Giastas and I. M. MarvidisPhotoreactions of  2- and 4-Pyridones in their Inclusion Crystal with a Host Compound”, J. Ηeterocyclic Chem. 2003, 59, 735-744.

  15.     P. Giastas, K. Yannakopoulou and I. M. MavridisMolecular structures of the inclusion complexes β-Cyclodextrin/1,2-bis(4-aminophenyl)ethane and  β-Cyclodextrin/4,4΄-diaminobiphenyl. Packing of dimeric β-Cyclodextrin inclusion complexes”, Acta Crystallogr. 2003, B59, 287-299.

  16.     N. Pinotsis, D. D. Leonidas, E. D. Chrysina, N. G. Oikonomakos, I. M. Mavridis “The binding of beta and gamma-cyclodextrins to glycogen phosphorylase b: kinetic and crystallographic studies” Protein Sci. 2003, 12, 1914-1924. Cover of the issue

  17.     K. Eliadou, P. Giastas, K. Yannakopoulou, I. M. MavridisSynthesis of 6-Mono-6-deoxy-β-cyclodextrins substituted with isomeric aminobenzoic acids. Structural Characterization, Conformational Preferences and Self-inclusion, as Studied by NMR Spectroscopy in Aqueous Solution, and by X-Ray Crystallography in the Solid State”, J. Org. Chem. 2003, 68, 8550-8557.

  18.    E. Hadjoudis  and I. M. Mavridis “Tautomerism by Hydrogen Transfer: the Case of Photochromic and Thermochromic Schiff-bases” Trends in Physical Chemistry 2003, 9, 141-149. Invited review.

  19.    N. Mourtzis, K. Eliadou, K. Yannakopoulou "Influence of Host’s Substitution on the Orientation of the Guest: Pseudo-rotaxanes of Charged Cyclo­dextrins with Methyl Orange in Solution, Supramolecular Chem. 2004,16, 587–593.

  20.     K. Yannakopoulou and I. M. Mavridis “Threading of long end-functionalised organic molecules into cyclodextrins: Structural analysis in aqueous solution by NMR spectroscopy and in the solid state by X-ray crystallography”, Current Org. Chem. 2004, 8, 25-34. Invited review.

  21.    F. Toda, K. Yoshizawa, S. Hyoda, S. Toyota,  S. Chatziefthimiou, I. M. Mavridis, “Efficient Resolution of 2,2’-Dihydroxy-1,1’-binaphthyl by Inclusion Complexation with Chiral N-(3-Chloro-2-hydroxypropyl)-N,N,N-trimethylammonium Chloride”, Org. Biomol. Chem. 2004, 2, 449-451.

  22.    P. Giastas, K. Eliadou, Z. F. Plyta, K. Yannakopoulou, and I. M. MavridisStructural Characterization of Per-6-bromo-2,3-di-O-acetyl-β-cyclodextrin, Studied in Solution by NMR Spectroscopy and in the Solid State as a Methanol Complex by X-Ray Crystallography. Unsusual glucopyranose conformations in the crystal” Carbohydr. Res. 2004, 339, 1189-1194.

  23.     E. Hadjoudis, A. Rontoyianni, K. Ambroziak, T. Dziembowska, I. M. Mavridis “Photochromism and Thermochromism of Solid trans- N,N΄- bis-(salicylidene)-1,2-cyclohexanediamines and trans-N,N΄-bis-(2-hydroxynaphthylidene) )-1,2-cyclohexanediamine” J. Photochem. Photobiol. A: Chem. 2004, 162, 521-530.

  24.    Ε. Hadjoudis, I. M. Mavridis  “Photochromism and Thermochromism of Schiff Bases in the Solid State: Structural Aspects” Chem. Soc. Rev. 2004, 33, 579- 588. Invited review.

[top of page]


  1.    K. Yoshizawa, S. Toyota, F. Toda, S. Chatziefthimiou, P. Giastas, I. M. Mavridis, M. Kato “A Novel Control of Differential Inclusion Complexation in the Solid State by Seed CrystalsAngew. Chem. Int. Ed. 2005, 44, 5097-5100.

  2.  D. Maffeo, L. Leondiadis, I. M. Mavridis, K. Yannakopoulou “Positive Effect of Natural and Negatively Charged Cyclodextrins on the Stabilization of Penicillins towards β-Lactamase Degradation due to Inclusion and External Guest-Host Association. An NMR and MS Study”, Org. Biomol. Chem. 2006, 4, 1297 – 1304.

  3.    P. Zou, N. Pinotsis, S. Lange, Y-H. Song, A. Popov, I. Mavridis, O. M. Mayans, M. Gautel, M. Wilmanns “Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk” Nature 2006, 439, 225-228.

  4.     K. Yannakopoulou, and I. M. MavridisRotaxane and Catenane Structures Involving Cyclodextrins” in the Handbook "Cyclodextrins and their Complexes. Chemistry, Analytical Methods & Applications" H. Dodziuk, Ed. 2006, p. 356-369, ISBN 3-527-31280-3 Wiley-VCH, Weinheim. Invited review

  5.    P. Giastas, N. Pinotsis, G. Efthymiou, M. Wilmanns, P. Kyritsis, J- M. Moulis, I. M. Mavridis “The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32 Å resolution. Comparison with other high resolution structures of ferredoxins and contributing structural features to reduction potential values”, J. Biolog. Inorg. Chem. 2006, 11, 445-458.

  6.     S. D. Chatziefthimiou, Y. G. Lazarou, E. Hadjoudis, T. Dziembowska and I. M. Mavridis “Stable cis-Keto Forms of Salicylaldehyde Schiff Bases:Structural and Theoretical Aspects”, J. Phys Chem. B 2006, 110, 23701-23709.

  7.   S. De Luca, M. Saviano, L. Lassiani, Yannakopoulou K., P. Stefanidou, L. Aloj, G. Morelli, A. Varnavas “Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their Receptor desmodynamic processes", J. Med. Chem. 2006, 49, 2456-2462.

  8.    R. Sears, E. Saridakis and N. E. Chayen “Experiment and theory for heterogeneous nucleation of protein crystals in a porous medium.” Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 597-601.

  9.   S. Stolyarova, E. Saridakis, N.E. Chayen & Y. Nemirovsky “A Model for Enhanced Nucleation of Protein Crystals on a Fractal Porous Substrate.” Biophys. J. 2006, 91, 3857-3863.

  10.    A.C. G. Hotze, Faiz JA, N. Mourtzis, G. I. Pascu, P. R. A Webber, G. J. Clarkson, K. Yannakopoulou, Z. Pikramenou, M. J. Hannon “Far-red luminescent ruthenium pyridylimine complexes; building blocks for multinuclear arrays”, Dalton Trans 2006 (24): 3025-3034.

  11.    M. Douvas, F. Van Roey, M. Goethals, K. Papadokostaki, K. Yannakopoulou, D. Niakoula, E. Gogolides, P. Argitis "Partially Fluorinated, POSS-functionalized (meth)acrylate Resists for 193nm-bilayer Lithography", Chem. Mater. 2006, 18, 4040-4048.

  12.    V. T. Karathanos, I. Mourtzinos, K. Yannakopoulou, N. K. Andrikopoulos “Study of the solubility, antioxidant activity and structure of inclusion complex of vanillin with β-cyclodextrin”, Food Chemistry, 2007, 101, 652.

  13.   N. Mourtzis, K. Eliadou, C. Aggelidou, V. Sophianopoulou, I. M. Mavridis, K. Yannakopoulou, “Synthesis and characterization of per(6-guanidino-6-deoxy)cyclodextrins and studies of their  effect on DNA”, Org. Biomol. Chem. 2007, 5, 125-131.

  14.    A.Paulidou, P. Giastas, N. Mourtzis, K. Yannakopoulou, I. M. Mavridis “Crystal and Molecular Structure of Octakis(6-bromo-6-deoxy)-γ-cyclodextrin. A novel stacking of a distorted macrocycle”, Carbohydr. Res. 2007, 342, 1519-1524.

  15.     S. D. Chatziefthimiou, K. Yannakopoulou, I. M. Mavridis “β-Cyclodextrin trimers enclosing an unusual organization of guest: The inclusion complex β-Cyclodextrin/4-pyridinealdazine” Cryst. Eng. Comm. 2007 9, 976-979.

  16.     I.Mourtzinos, F. Salta, K. Yannakopoulou, A. Chiou, V. T. Karathanos “Encapsulation of olive leaf extract in β-Cyclodextrin”, J. Agr. Food Chem.  2007, 55, 8088-8094.

  17.    I.  Mourtzinos, D. P. Makris, K. Yannakopoulou, N. Kalogeropoulos, I. Michali, V. T. Karathanos, J. Agric. Food Chem. 2008, 56, 10303–10310.

  18.    N. Mourtzis, M. Paravatou, I. M. Mavridis, M. L. Roberts, K. Yannakopoulou Synthesis, characterisation, and remarkable biological properties of cyclodextrins bearing guanidino-alkylamino and aminoalkylamino groups on their primary side”, Chem. Eur. J. 2008, 14, 4188-4200.

  19.    A.Paulidou, D. Maffeo, K. Yannakopoulou, I M. Mavridis “Crystal structure of the inclusion complex of the antibacterial agent triclosan in β-cyclodextrin and NMR study of its molecular encapsulation in positively and negatively charged cyclodextrins” Carbohydr. Res. 2008, 343, 2634-2640.

  20.     D. Velessiotis, D. Maffeo, E. Makarona, C. Viswanathan, K. Yannakopoulou, I. Mavridis, Z. Pikramenou, and N. Glezos “Molecular Nanodevices based on Functionalized Cyclodextrins”, Phys. Stat. Solid. 2008, 205, 2532-2535.

  21.    N. E. Chayen and E. Saridakis “Protein crystallization: from purified protein to diffraction-quality crystal.” Nature Methods 2008, 5, 147-153.    

  22. E. Hadjoudis, S. D. Chatziefthimiou, I. M. Mavridis, “Anils: Photochromism by H-transfer”, Current Org. Chem. 2009, 13, 269-286. Invited review

  23.     C. Aggelidou, I. M. Mavridis, K. Yannakopoulou “Binding of nucleotides and nucleosides to per(6-guanidino-6-deoxy)-cyclodextrins in solution” , Eur. J. Org. Chem. 2009, 2299-2305.

  24.      E. Saridakis, P. Giastas, G. Efthymiou,2 V. Thoma, J-M. Moulis, P. Kyritsis, I. M. Mavridis ”Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: Crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin” J. Biolog. Inorg. Chem. 2009, 14, 783-799.

  25.    E. Saridakis and N. E. Chayen “Towards a ‘universal’ nucleant for protein crystallization.” Trends Biotechnol.  2009, 27, 99-106.

  26.  P. Asanithi, E. Saridakis, L. Govada, I. Jurewicz, E.W. Brunner, R. Ponnusamy, J.A.S. Cleaver,  A.B. Dalton, N.E. Chayen, R.P. Sear, “Carbon-nanotube based materials for protein crystallisation.” ACS Appl. Mat. Interf. 2009, 1, 1203-1210.

  27. A. Paulidou, D. Maffeo, K. Yannakopoulou, I.M. Mavridis Similar modes of inclusion in complexes of β-cyclodextrin with sulfonylurea hypoglycemic drugs” Cryst. Eng. Comm. 2010, 12, 517–525.

  28. D. Maffeo, M. Lampropoulou, M. Fardis, Y. G. Lazarou, I. M. Mavridis, D. A.I. Mavridou, E. Urso, H. Pratsinis, D. Kletsas, K. Yannakopoulou, “Novel Polycarboxylated EDTA-Type Cyclodextrins as Ligands for Lanthanide Binding: Study of Their Luminescence, Relaxivity Properties of Gd(III) Complexes, and PM3 Theoretical Calculations” Org. Biomol. Chem. 2010, 8, 1910-1921.

  29. N. Kalogeropoulos, K. Yannakopoulou, A. Gioxari, A. Chiou, D. P Makris, “Polyphenol characterization and encapsulation in β-cyclodextrin of a flavonoid-rich Hypericum perforatum (St John's wort) extract “ LWT- Food Science and Technology, 2010, 43, 882-889.

  30. A. Paulidou, K. Yannakopoulou, I. M. Mavridis, “Hydrolysis of glutaric anhydride to glutaric acid in the presence of β-cyclodextrin. Crystallographic and NMR study”, J Incl. Phenom. Macrocycl. Chem. 2010, 68, 297–303 ().

  31.   A. Douvas, K. Yannakopoulou, P. Argitis "Thermally-Induced Acid Generation from 18-Molybdodiphosphate and 18-Tungstodiphosphate within Poly(2-Hydroxyethyl Methacrylate) Films" Chem. Mater., 2010, 22 (9): 2730-2740.

  32. A. Kaloudi-Chantzea, N. Karakostas, C.P. Raptopoulou, V. Psycharis, E. Saridakis, J. Griebel, R. Hermann and G. Pistolis. “Coordination-driven self assembly of a brilliantly fluorescent rhomboid cavitand composed of bodipy-dye subunits.” J. Am. Chem. Soc. (2010) 132, 16327-16329.

  33. A. Garcia-Caballero, J.A. Gavira, E. Pineda-Molina, N.E. Chayen, L. Govada, S. Khurshid, E. Saridakis, A. Boudjemline, M.J. Swann, P. Shaw Stewart, R.A. Briggs, S.A. Kolek, D. Oberthuer, K. Dierks, C. Betzel, M. Santana, J.R. Hobbs, P. Thaw, T.J. Savill,  J.R. Mesters, R. Hilgenfeld, N. Bonander and R.M. Bill. “Optimization of Protein Crystallization: The OptiCryst Project.” Cryst. Growth Des. (2011) 11, 2112–2121.

  34. E. Hadjoudis, K. Yannakopoulou, S. D. Chatziefthimiou, A. Paulidou, I. M. Mavridis Supramolecular Control of Photochromism in a β-Cyclodextrin/Schiff Base System J Photochem. Photobiol. A: Chem. 217, 293–298 (2011).

  35. D. Maffeo, Z. Velkov, K. Misiakos, K. Mergia, A. Paulidou, M. Zavali, I. M. Mavridis, K. YannakopoulouReal Time Nanomolar Detection of Triclosan Binding to an Amphiphilic Cyclodextrin Immobilised on a Surface using White Light Reflectometry J Colloid Interf. Sci. 358, 369-375 (2011).

  36. K. Fotiadou, A. Thanassoulas, G. Nounesis, K. Yannakopoulou "Cooperative Heterodimer Formation Between Per-Guadinylated and Carboxylated or Phoshporylated Cyclodextrins in DMSO and DMSO-Water Studied by NMR Spectroscopy and Microcalorimetry”, , Supramol. Chem., 2011, 23(17), 493-500.

  37. K. Yannakopoulou, L. Jicsinszky, C. Aggelidou, N. Mourtzis, T. M. Robinson, A. Yohannes, E. M. Nestorovich, S. Bezrukov, V. A. Karginov "Symmetry requirements for the effective blocking of pore-forming toxins: Comparative study with α-, β-, and γ-cyclodextrin derivatives” Antimicrob. Agents Chemother. (AAC), 2011, 55, 3594-3597.

  38. M. Lampropoulou, K. Yannakopoulou "Synthesis and characterisation of novel glycoclusters based on cell penetrating heptakis(6-aminoethylamino-6-deoxy)-β-cyclodextrin” J. Incl. Phen. Macrocycl. Chem, 2011,70, 345-352.

  39.  I. Balomenou, A. Kaloudi-Chantzea, N. Karakostas, K. Yannakopoulou, I. M. Mavridis, G Pistolis "Controlling the Stereospecificity of a Volume-Conserving Adiabatic Photoisomerization within a Nanotubular Self-Assembled Cage: A Reversible Light_Heat Torque Converter", J Phys. Chem. B. 2011 115, 10665-10681.

  40. A. Boudjemline, E. Saridakis, M. J. Swann, L. Govada, I. M. Mavridis, N. E. Chayen "Use of Dual Polarisation Interferometry as a diagnostic tool for protein crystallisation", Anal. Chem. 2011, 83, 7881-7887.

  41. D.A.I. Mavridou, E. Saridakis, P. Kritsiligkou, A.D. Goddard, J.M. Stevens, S.J. Ferguson and C. Redfield. “Oxidation-state-dependent protein-protein interactions in disulfide cascades.” J. Biol. Chem. 2011, 286, 24943-24956.

  42. I.A. Katsoulis, G. Kythreoti, A. Papakyriakou, K. Koltsida, P. Anastasopoulou, C.I. Stathakis, I. Mavridis, T. Cottin, E. Saridakis and D. Vourloumis. “Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A-site.” ChemBioChem 2011, 12, 1188-1192.

  43. E. Saridakis. “A novel Genetic Algorithm-inspired concept for macromolecular crystal optimisation.” Crystal Growth Des. 2011, 11, 2993-2998.

  44. E. Saridakis, S. Khurshid, L. Govada, Q. Phan, D. Hawkins, G.V. Crichlow, E. Lolis, S.M. Reddy and N.E. Chayen. “Protein crystallization facilitated by molecularly imprinted polymers.” Proc. Natl. Acad. Sci. USA 2011, 108, 11081-11086.

  45. E. SaridakisPerspectives on high-throughput technologies applied to protein crystallisation.” Protein Pept. Lett.  2012, 19, 778-783.

  46. J. R. Birtley, E. Saridakis, E. Stratikos, I. M. Mavridis "Crystal Structure of Human ER Aminopeptidase 2 Reveals Atomic Basis for Distinct Roles in Antigen Processing" Biochemistry 2012, 51, 286–295.

  47. N. Pinotsis, S. D. Chatziefthimiou, F. Berkemeier, F. Beuron, I. M. Mavridis, P. V. Konarev, D. I. Svergun, E. Morris, M. Rief, M. Wilmanns "Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties" PLoS Biol. 2012, Feb;10(2):e1001261.

  48.  I. Evnouchidou, J. Birtley, S. Seregin, A. Papakyriakou, E. Zervoudi, M. Samiotaki, G. Panayotou, P. Giastas, O. Petrakis, D. Georgiadis, A. Amalfitano,  E. Saridakis, I. M. Mavridis, E. Stratikos “A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch that Leads to Altered Antigen Processing” J. Immunol. 2012, 189, 2383-2392.

  49. L. E. P. Kyllönen, V. Chinuswamy, D. Maffeo, E. T. Kefalas, J. M. Haider, Z. Pikramenou, I. M. Mavridis, K. Yannakopoulou, N. GlezosElectronic transport between Au surface and STM tip via a multipodal cyclodextrin host - metallo-guest supramolecular system”, J Phys. Org. Chem. 2012, 25, 198206.

  50. Tamoxifen Subcellular Localization; Observation of Cell-specific Cytotoxicity Enhancement by Inhibition of Mitochondrial ETC Complexes I and III", T. A. Theodossiou, K. Yannakopoulou, C. Aggelidou and J. S. Hothersall, Photochem. Photobiol. 2012, 88(4), 1016-1022.

  51. K. Yannakopoulou "Cationic Cyclodextrins: Cell Penetrating Agents and Other Diverse Applications”,  J. Drug Del. Sci. Tech. 2012, 22 (3) 243-249.

[top of page]


  1.  L. Piras, T. A. Theodossiou, M. D. Manouilidou, S. Sortino, K. Yannakopoulou "S-Nitroso-β-Cyclodextrins as Novel Bimodal Carriers: Preparation, Detailed Characterization, Nitric Oxide Release and Molecular Encapsulation"  Chem. Asian J. 2013, 8(11), 2768-2778.

  2. A. Fraix, Antonio R. L. Gonçalves, V. Cardile, A. C. E. Graziano, T. A. Theodossiou, K. Yannakopoulou, S. Sortino "A Multifunctional Bichromophoric Nanoaggregate for Fluorescence Imaging and Simultaneous Photogeneration of RNOS and ROS” , Chem. Asian J. 2013, 8(11), 2634-2641.

  3. C. Aggelidou, T. A. Theodossiou, K. Yannakopoulou "Protoporphyrin IX-β-Cyclodextrin Bimodal Conjugate: Nanosized Drug Transporter and Potent Phototoxin",  Photochem. Photobiol. 2013, 89, 1011-1019.

  4. E. Saridakis and Naomi E. Chayen. “Imprinted polymers assisting protein crystallization.” Trends Biotechnol. 2013, 31, 515-520.

  5. E. Zervoudi, E. Saridakis, J.R. Birtley, S. Seregin , E. Reeves, P. Kokkala, Y.A. Aldhamen, A. Amalfitano, I.M. Mavridis, E. James, D. Georgiadis and E. Stratikos (2013) “A rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses.” Proc. Natl. Acad. Sci. USA 2013 110, 19890-19895.

  6. N. Karakostas, I. M. Mavridis, K. Seintis, M. Fakis, E. N. Koini, I. D. Petsalakis, G. Pistoli "Highly efficient and unidirectional energy transfer within a tightly self-assembled host–guest multichromophoric array", Chem. Commun., 2014, 50 (11), 1362 - 1365


[top of page]