Laboratory of Structural & Supramolecular Chemistry

Research Projects

 

References: B.  Synthesis of functional cyclodextrin derivatives and applications

 

1. K. Eliadou, P. Giastas, K. Yannakopoulou, I. M. MavridisSynthesis of 6-Mono-6-deoxy-β-cyclodextrins substituted with isomeric aminobenzoic acids. Structural Characterization, Conformational Preferences and Self-inclusion, as Studied by NMR Spectroscopy in Aqueous Solution, and by X-Ray Crystallography in the Solid State”, J. Org. Chem. 2003, 68, 8550-8557.

 2. P. Giastas, K. Eliadou, Z. F. Plyta, K. Yannakopoulou, and I. M. MavridisStructural Characterization of Per-6-bromo-2,3-di-O-acetyl-β-cyclodextrin, Studied in Solution by NMR Spectroscopy and in the Solid State as a Methanol Complex by X-Ray Crystallography. Unsusual glucopyranose conformations in the crystal” Carbohydr. Res., 2004, 339, 1189-1194.

 3. A. Paulidou, P. Giastas, N. Mourtzis, K. Yannakopoulou, I. M. Mavridis “Crystal and Molecular Structure of Octakis(6-bromo-6-deoxy)-γ-cyclodextrin. A novel stacking of a distorted macrocycle”, Carbohydr. Res., 2007, 342, 1519-1524.

 4. D. Maffeo, L. Leondiadis, I. M. Mavridis, K. Yannakopoulou, “Positive Effect of Natural and Negatively Charged Cyclodextrins on the Stabilization of Penicillins towards β-Lactamase Degradation due to Inclusion and External Guest-Host Association. An NMR and MS Study”, Org. Biomolec. Chem. 2006, 4 (7), 1297-1304.

 5. N. Mourtzis, K. Eliadou, K. Yannakopoulou "Influence of Host’s Substitution on the Orientation of the Guest: Pseudo-rotaxanes of Charged Cyclo­dextrins with Methyl Orange in Solution.” N. Mourtzis, K. Eliadou, K. Yannakopoulou, Supramolecular Chem. 2004,16 (8), 587–593.

 6. N. Mourtzis, K. Eliadou, C. Aggelidou, V. Sophianopoulou, I. M. Mavridis, K. Yannakopoulou, “Synthesis and characterization of per(6-guanidino-6-deoxy)cyclodextrins and studies of their  effect on DNA”, Org. Biomol. Chem. 2007, 5, 125-131.

 7. N. Mourtzis, M. Paravatou, I. M. Mavridis, M. L. Roberts, K. Yannakopoulou Synthesis, characterisation, and remarkable biological properties of cyclodextrins bearing guanidino-alkylamino and aminoalkylamino groups on their primary side”, Chem.Eur. J. 2008 14, 4188-4200.

 8. C. Aggelidou,  I. M. Mavridis, K. Yannakopoulou “Binding of nucleotides and nucleosides to per(6-guanidino-6-deoxy)-cyclodextrins in solution” , Eur. J. Org. Chem. 2009, 2299-2305.

 9. EDTA-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium(IΙI) for use in magnetic resonance imaging, D. Maffeo, M. Lampropoulou, G. Fardis, I. M. Mavridis, K. Yannakopoulou, Greek patent application, priority date 22 Sept. 2009.

 10. M. Lampropoulou, K. Yannakopoulou , “Novel Sugar-Functionalised Cyclodextrins and Studies On Molecular Inclusion of Model Compounds”, 2nd EuCheMS Chemistry Congress:Chemistry, the Global Science, September 16-20, 2008, Torino, Italy.

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