Research Projects
References:
B. Synthesis
of
functional cyclodextrin derivatives
and applications
1. K.
Eliadou, P. Giastas, K. Yannakopoulou,
I. M. Mavridis “Synthesis
of 6-Mono-6-deoxy-β-cyclodextrins
substituted with isomeric aminobenzoic acids.
Structural
Characterization, Conformational Preferences and Self-inclusion, as
Studied by NMR Spectroscopy in Aqueous Solution, and by X-Ray
Crystallography in the Solid
State”, J. Org. Chem.
2003, 68,
8550-8557.
2. P. Giastas, K. Eliadou,
Z. F.
Plyta, K. Yannakopoulou, and I.
M. Mavridis “Structural
Characterization of Per-6-bromo-2,3-di-O-acetyl-β-cyclodextrin,
Studied in Solution by NMR Spectroscopy and in the Solid State as a
Methanol Complex by X-Ray Crystallography. Unsusual glucopyranose
conformations in the crystal”
Carbohydr.
Res.,
2004, 339, 1189-1194.
3. A. Paulidou, P. Giastas, N. Mourtzis,
K. Yannakopoulou, I. M. Mavridis “Crystal
and Molecular Structure of Octakis(6-bromo-6-deoxy)-γ-cyclodextrin.
A novel stacking of a distorted macrocycle”,
Carbohydr.
Res.,
2007,
342, 1519-1524.
4.
D. Maffeo, L. Leondiadis, I. M. Mavridis, K. Yannakopoulou, “Positive
Effect of Natural and Negatively Charged Cyclodextrins on the
Stabilization of Penicillins towards
β-Lactamase
Degradation due to Inclusion and External Guest-Host Association. An NMR
and MS Study”,
Org. Biomolec. Chem.
2006,
4 (7),
1297-1304.
5.
N. Mourtzis, K. Eliadou, K. Yannakopoulou
"Influence of Host’s
Substitution on the Orientation of the Guest: Pseudo-rotaxanes of
Charged Cyclodextrins with Methyl Orange in Solution.”
N. Mourtzis, K. Eliadou,
K. Yannakopoulou,
Supramolecular Chem. 2004,16 (8), 587–593.
6. N. Mourtzis, K. Eliadou, C. Aggelidou, V. Sophianopoulou,
I. M. Mavridis,
K. Yannakopoulou, “Synthesis and characterization of
per(6-guanidino-6-deoxy)cyclodextrins and studies of their
effect on DNA”, Org.
Biomol. Chem. 2007, 5,
125-131.
7.
N. Mourtzis, M. Paravatou, I. M. Mavridis, M. L. Roberts, K.
Yannakopoulou “Synthesis,
characterisation, and remarkable biological properties of cyclodextrins
bearing guanidino-alkylamino and aminoalkylamino groups on their primary
side”,
Chem.Eur. J.
2008,
14, 4188-4200.
8.
K. Yannakopoulou, L. Jicsinszky, C. Aggelidou, N.
Mourtzis, T. M. Robinson, A. Yohannes, E. M. Nestorovich, S.
Bezrukov4, V. A. Karginov
“Symmetry requirements for the effective blocking of pore-forming
toxins: Comparative study with α-, β-, and γ-cyclodextrin derivatives”,
Antimicrob.
Agents Chemother. (AAC),
2011,
55, 3594-3597.
9.
K.
Yannakopoulou
“Cationic
Cyclodextrins: Cell Penetrating Agents and Other Diverse Applications”,
J. Drug Del.
Sci. Tech.,
2012,
22,
243-249 (review article).
10.
D. Maffeo, M. Lampropoulou, M. Fardis,
Y. G. Lazarou, I. M. Mavridis,
D. A.I. Mavridou, E. Urso,
H. Pratsinis, D. Kletsas, K. Yannakopoulou,
“Novel Polycarboxylated EDTA-Type Cyclodextrins as Ligands for
Lanthanide Binding: Study of Their Luminescence, Relaxivity Properties
of Gd(III) Complexes, and PM3 Theoretical Calculations”,
Org. Biomol.
Chem.
2010,
8,
1910-1921.
11.
M. Lampropoulou, K. Yannakopoulou
“Synthesis and characterisation of novel glycoclusters based on cell
penetrating heptakis(6-aminoethylamino-6-deoxy)-β-cyclodextrin”,
J. Incl. Phen. Macrocycl. Chem,
2011,70,
345-352.
12.
D. Maffeo, Z. Velkov, K. Misiakos, K. Mergia,
A. Paulidou, M. Zavali, I. M. Mavridis, K. Yannakopoulou
“Real Time Monitoring of
Nanomolar Binding To a Cyclodextrin Monolayer Immobilised on a Si/SiO2/Novolac
Surface Using White Light Reflectance Spectroscopy: The Case of
Triclosan”,
J. Colloid. Interface Sci.
2011,
358,
369–375.
13.
L. E. P. Kyllönen,
V. Chinuswamy,
D. Maffeo, E..T. Kefalas, J. M. Haider, Z.
Pikramenou, I. M. Mavridis, K. Yannakopoulou,
N. Glezos
“Electronic transport between Au surface and
STM tip via a multipodal cyclodextrin host - metallo-guest
supramolecular system” ,
J. Phys. Org. Chem. 2012,
25,
198–206.
14.
A. Fraix,
Antonio R. L. Gonçalves, V. Cardile, A. C. E. Graziano, T. A.
Theodossiou, K. Yannakopoulou and S. Sortino
"A
Multifunctional Bichromophoric Nanoaggregate for Fluorescence
Imaging and Simultaneous Photogeneration of RNOS and ROS”,
Chem. Asian J.
2013,
8, 2634-2641.
15.
C. Aggelidou, T. A. Theodossiou, K. Yannakopoulou
"Protoporphyrin
IX-β-Cyclodextrin Bimodal Conjugate: Nanosized Drug Transporter and
Potent Phototoxin", Photochem.
Photobiol.,
2013,
89, 1011-1019.
16.
L.
Piras, T. A. Theodossiou, M. D. Manouilidou, S. Sortino, K.
Yannakopoulou
"S-Nitroso-β-Cyclodextrins
as Novel Bimodal Carriers: Preparation, Detailed Characterization,
Nitric Oxide Release and Molecular Encapsulation", Chem. Asian J.
2013,
8(11), 2768-2778.
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